AdipoUpX™ Human IGF1 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human IGF1 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle designed for the long-lasting overexpression of the human IGF1 gene. As a major mediator of growth hormone action, its stable expression in cell models allows for in-depth research into its anabolic effects and its role in adipose tissue expansion. To ensure experimental reproducibility, the product undergoes comprehensive quality control, including titer and mycoplasma testing. Researchers can flexibly choose report genes for precise multifunctional validation.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: IGF1

Full Name: Insulin like growth factor 1

Gene Symbol: IGF; MGF; IGFI; IGF-I

Gene ID: 3479

RefSeq ID-1: NP_000609.1

RefSeq ID-2: NM_000618.5

Summary: IGF1 encodes a protein structurally and functionally similar to insulin and belongs to a family of proteins involved in growth and development. The protein is synthesized as a precursor, processed into its mature form, secreted, and binds to a specific receptor to exert its effects. Mutations in IGF1 cause insulin-like growth factor I deficiency. Alternative splicing generates multiple transcript variants encoding different isoforms, which may undergo similar processing to yield functional proteins.

AdipoUpX™ Human IGF1 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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