AdipoUpX™ Human CNR1 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CNR1 MMLV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human CNR1 (CB1 receptor) gene. The cannabinoid receptor 1 is a central target in appetite stimulation and peripheral lipid metabolism. Stable integration into dividing cells allows for the systematic investigation of downstream signaling and pharmacological modulation. Product quality is ensured by rigorous purification and comprehensive QC screening, guaranteeing both safety and the highest standards for neuro-metabolic research.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: CNR1

Full Name: Cannabinoid receptor 1

Gene Symbol: CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5

Gene ID: 1268

RefSeq ID-1: NP_001153698.1

RefSeq ID-2: NM_001160226.3

Summary: CNR1 encodes the CB1 receptor, a G-protein-coupled receptor (GPCR) that mediates the effects of cannabinoids. These receptors inhibit adenylate cyclase and modulate various neurotransmitter release patterns in the brain. Beyond its well-known effects on mood and cognition, the CNR1 signaling system is a potent regulator of energy balance and appetite. Over-activation of these receptors in the brain and peripheral tissues is frequently associated with increased food intake and the accumulation of body fat.

AdipoUpX™ Human CNR1 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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