AdipoUpX™ Human CCKAR MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CCKAR MSCV Particle (Overexpression) is designed for stable expression of the human CCKAR gene, encoding the cholecystokinin A receptor. CCKAR mediates satiety signaling and gastrointestinal hormone responses that influence food intake and body weight regulation. The MSCV retroviral system supports durable gene expression across stem cells and other mammalian cell lines relevant to obesity research. Comprehensive QC, including titer, sterility, and mycoplasma testing, is performed to ensure reliable results.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: CCKAR

Full Name: Cholecystokinin A receptor

Gene Symbol: CCK-A; CCK1R; CCKRA; CCK-1R; CCK1-R

Gene ID: 886

RefSeq ID-1: NP_000721.1

RefSeq ID-2: NM_000730.3

Summary: The CCKAR gene encodes a G-protein-coupled receptor that responds to cholecystokinin (CCK), a peptide hormone. While it is a major driver of gallbladder contraction and pancreatic secretion, its role in the nervous system is equally critical. By regulating satiety signals in the brain, CCKAR acts as a physiological mediator of appetite control and post-meal fullness.

AdipoUpX™ Human CCKAR MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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