AdipoUpX™ Human STAT1 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human STAT1 MSCV Particle (Overexpression) is engineered for stable overexpression of the human STAT1 transcription factor, a key mediator of cytokine and interferon signaling. STAT1 activity influences inflammatory pathways that contribute to insulin resistance and obesity-associated metabolic dysfunction. The MSCV retroviral system supports long-term expression in stem cells and diverse mammalian cell models. Each product batch is released only after thorough quality control testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: STAT1

Full Name: Signal transducer and activator of transcription 1

Gene Symbol: CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Gene ID: 6772

RefSeq ID-1: NP_009330.1

RefSeq ID-2: NM_007315.4

Summary: STAT1 encodes a signal transducer and transcriptional activator that mediates cellular responses to cytokines and growth factors, particularly interferons. Upon activation, STAT1 regulates genes involved in immunity, stress responses, and cell survival. Chronic STAT1 signaling has been associated with inflammatory states that intersect with metabolic dysfunction, linking immune activation to obesity-related insulin resistance.

AdipoUpX™ Human STAT1 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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