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AdipoUpX™ Human CCK AAV Particle (Overexpression)
Cat. No.:
V1225XX272
Species:
Human
Target Gene:
CCK
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX272-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX272-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX272-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX272-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX272-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX272-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX272-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX272-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX272-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX272-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human CCK AAV Particle (Overexpression) is a high-titer AAV product that ensures efficient and stable expression of the human CCK gene. Specifically designed for validating the role of this gut hormone in satiety signaling and appetite suppression, it serves as a reliable tool for accelerating endocrinology research. Our customizable platform allows flexible selection of serotypes and fluorescent labels for targeted delivery, supported by rigorous internal quality control including titer and mycoplasma detection.
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
CCK
Full Name:
Cholecystokinin
Gene ID:
885
RefSeq ID-1:
NP_000720.1
RefSeq ID-2:
NM_000729.6
Summary:
The CCK gene produces a preproprotein that undergoes specific proteolytic cleavage to yield several active peptide hormones, such as CCK-8 and CCK-33. These peptides act as indispensable satiety signals by regulating gastric acid secretion and slowing digestion. In the central nervous system, sulfated CCK-8 modulates neuronal activity to inhibit food intake. Because it directly bridges gut signaling with brain behavior, CCK is a foundational gene in the study of appetite regulation and obesity.
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