AdipoUpX™ Human ADIPOQ Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ADIPOQ Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human ADIPOQ gene. ADIPOQ codes for Adiponectin, a circulating adipokine that acts as a systemic protector of metabolic health. Its stable overexpression enables researchers to study ADIPOQ's insulin-sensitizing and anti-inflammatory roles. The lentivirus characteristic of genome integration establishes reliable cell models. Clients can freely customize key functional components to meet diverse experimental needs.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: ADIPOQ

Full Name: Adiponectin, C1Q and collagen domain containing

Gene Symbol: ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1

Gene ID: 9370

RefSeq ID: NM_001177800.2, NP_001171271.1

Summary: ADIPOQ exclusively codes for adiponectin, a unique adipokine structurally resembling collagen and complement factor C1q. This protein circulates abundantly in plasma and functions as a protective signal from fat tissue. Its action enhances insulin sensitivity and promotes fatty acid oxidation in muscle and liver, actively counteracting insulin resistance. Adiponectin levels are typically inversely proportional to body fat mass and are considered a major metabolic marker. Deficiencies in the ADIPOQ protein are clinically linked to severe metabolic dysfunctions, including type 2 diabetes and cardiovascular risk.

AdipoUpX™ Human ADIPOQ Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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