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Telaglenastat
Cat. No.:
OB0225LY-0471
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Telaglenastat is an agent that inhibits glutamine metabolism and is designed to enhance antitumor activity.
Synonym:
CB 839; CB839; CB-839; 1439399-58-2; 2-(Pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol-2-yl)acetamide; N-[6-[4-[5-[(2-Pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide; N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-2-pyridineacetamide
CAS No.:
1439399-58-2
Compound CID:
71577426
Formula:
C26H24F3N7O3S
Formula Weight:
571.57
Specification
Relative Density:
1.430 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Telaglenastat can be used in cancer research or play an important role in studies related to metabolic remodeling.
Library Information
Targets:
Transporter; Glutaminase
Receptors:
GLS1
Pathways:
Autophagy; Metabolism; Proteases/Proteasome
Plate Number:
AOCL-7
Plate Location:
a9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
60 mg/mL
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 9.3 mg/mL (16.27 mM)
ALogP:
5.597
HBA_Count:
8
HBD_Count:
2
Rotatable Bond:
13
