Plerixafor octahydrochloride

Cat. No.: 0225LY-1151

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Plerixafor octahydrochloride acts as a bicyclam with potent hematopoietic stem cell-mobilizing properties; it facilitates the release of these cells from the bone marrow into peripheral circulation by blocking the interaction between the SDF-1alpha ligand and the CXCR4 receptor.

Synonym: JM3100 octahydrochloride; Plerixafor 8HCl (AMD3100 8HCl); Plerixafor 8HCl; SID791 octahydrochloride; AMD 3100 octahydrochloride; JM 3100 8HCl; 155148-31-5; Plerixafor hcl; Sid 791; JM 3100; 1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene octahydrochloride; Plerixafor hydrochloride; Plerixafor (octahydrochloride); AMD-3100; AMD3100 octahydrochloride hydrate; SDZ-SID-791; Bicyclam; Plerixafor Hydrochloride (1:8); 1,1'-(1,4-Phenylenebis(methylene))bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride; 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride; 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;octahydrochloride

CAS No.: 155148-31-5

Compound CID: 65014

Formula: C₂₈H₆₂Cl₈N₈

Formula Weight: 794.46

Specification

Targets&IC50: CXCL12: 5.7 nM; CXCR4: 44 nM

Relative Density: 0.962 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Plerixafor octahydrochloride can be used in hematology research to study the mobilization of hematopoietic stem cells through CXCR4 antagonism.