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MK-2206 dihydrochloride
Cat. No.:
OB0225LY-0298
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
MK-2206 dihydrochloride is a selective Akt inhibitor that interferes with cell growth and survival signaling pathways.
Synonym:
MK-2206 2HCl; 1032350-13-2; MK-2206; 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one; 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one; 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
CAS No.:
1032350-13-2
Compound CID:
24964624
Formula:
C25H23Cl2N5O
Formula Weight:
480.39
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
MK-2206 dihydrochloride can be used to study the regulation of the PI3K/Akt pathway or play an important role in tumor metabolism research.
Library Information
Targets:
Akt family
Receptors:
Akt1; Akt2; Akt3
Pathways:
PI3K/Akt/mTOR signaling; Apoptosis; Autophagy; Cytoskeletal signaling
Plate Number:
AOCL-4
Plate Location:
g9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
7.5 mg/mL; 15.61 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Solubility:
10% DMSO+90% Saline: 0.75 mg/mL (1.56 mM)
ALogP:
4.183
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
3
