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TWS119
Cat. No.:
OB0225LY-0310
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
TWS119 is a small molecule inhibitor that acts primarily on GSK-3β and is involved in multiple cell signaling pathways.
Synonym:
601514-19-6; TWS-119; 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol; GSK inhibitor XII; 3-(6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)phenol; 3-{[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}phenol
CAS No.:
601514-19-6
Compound CID:
9549289
Formula:
C18H14N4O2
Formula Weight:
318.33
Specification
Relative Density:
1.415 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TWS119 can be used to study the mechanisms of glycogen synthesis and cell fate determination, as well as its important role in stem cell biology.
Library Information
Targets:
GSK-3 family
Receptors:
GSK-3β
Pathways:
PI3K/Akt/mTOR signaling; Autophagy; Stem cells
Plate Number:
AOCL-5
Plate Location:
a3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
60 mg/mL; 188.48 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
