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GSK621
Cat. No.:
OB0225LY-0360
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
GSK621 is a small molecule compound used to specifically inhibit the mTOR signaling pathway and study its effects on cell growth.
Synonym:
1346607-05-3; 6-Chloro-5-[4-(2-hydroxy-3-methoxyphenyl)phenyl]-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4-dione; 6-Chloro-5-{2'-hydroxy-3'-methoxy-[1,1'-biphenyl]-4-yl}-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4-dione; 6-Chloro-5-(2'-hydroxy-3'-methoxy-[1,1'-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione
CAS No.:
1346607-05-3
Compound CID:
54577153
Formula:
C26H20ClN3O5
Formula Weight:
489.91
Specification
Relative Density:
1.41 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GSK621 can be used to study muscle growth and metabolic pathways.
Library Information
Targets:
AMPK
Pathways:
PI3K/Akt/mTOR signaling; Apoptosis; Autophagy; Chromatin/Epigenetic
Plate Number:
AOCL-5
Plate Location:
f5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
90 mg/mL; 183.7 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
5.217
HBA_Count:
4
HBD_Count:
2
Rotatable Bond:
5
