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PI-103
Cat. No.:
OB0225LY-0403
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
PI-103 is a dual-targeted PI3K and mTOR inhibitor widely used in signal transduction studies.
Synonym:
PI103; PI 103; 371935-74-9; 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol; Phenol, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-; 3-[4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol; 3-[6-(Morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-4-yl]phenol
CAS No.:
371935-74-9
Compound CID:
9884685
Formula:
C19H16N4O3
Formula Weight:
348.36
Specification
Relative Density:
1.409 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PI-103 can be used to study the key role of the PI3K/mTOR pathway in cellular metabolism and proliferation.
Library Information
Targets:
PIKKs; PI3K class I subunits
Receptors:
DNA-PK; mTOR; p110α; p110β; p110γ; p110δ
Pathways:
PI3K/Akt/mTOR signaling; Autophagy; Apoptosis; DNA damage/DNA repair
Plate Number:
AOCL-6
Plate Location:
b9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
5 mg/mL; 14.35 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
2.798
HBA_Count:
5
HBD_Count:
1
Rotatable Bond:
2
