LipoKnoxa™ Human SERPINA12 shRNA Lentiviral Particle (Silencing)

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX545-1	CACGGTGAAAGGTCTTCTAAA	CDS	Inquiry
V0126XX545-2	TTAACAACCTGATCGAGAATA	CDS	Inquiry
V0126XX545-3	ATGTTCCGTAGTGGCATATAC	CDS	Inquiry
V0126XX545-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human SERPINA12 shRNA Lentiviral Particle (Silencing) targets vaspin, an adipokine that improves insulin sensitivity. Engineered via our dual-strategy platform (U6 and miR30 systems), this tool enables researchers to investigate metabolic syndrome mechanisms. Every preparation is verified via thorough QC validation—including functional activity and microbial purity checks.

Production Cell Line: HEK293T

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Comprehensive sequencing and PCR analyses were performed to verify the accurate genomic sequence of all viral preparations.

Sterility Test: Confirmed sterile via rigorous microbial analysis; free of bacterial and fungal contamination.

Mycoplasma Test: Rigorous quality control testing has confirmed the absence of mycoplasma contamination in this viral preparation.

Other QC: Customized supplementary testing and in vitro/in vivo assessments are available to verify post-silencing gene expression and biological functionality, ensuring the viral preparations meet the specific potency requirements of your gene interference project.

Storage: Store at -80°C for long-term preservation. Immediate transfer upon delivery is required to prevent loss of viral activity.

Stability: Shelf life: 6–12 months at -80°C (extended stability up to 2 years). Post-thaw: Stable at 4°C for 2–3 weeks without significant degradation of functional titers.

Shipping Condition: Products are delivered on dry ice to maintain the cold chain. Upon arrival, please ensure the presence of dry ice and transfer the vials immediately to -80°C storage.

Handling Notes: Avoid repeated freeze-thaw cycles. Aliquot into low-protein-binding tubes immediately after receipt to maintain optimal activity. For safety and contamination control, all viral handling must be performed inside a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: We ensure product integrity through rigorous QC, but we do not guarantee results in specific research contexts. Proper storage, handling, and total compliance with biosafety laws and safety protocols remain the sole responsibility of the user.

Target Profile

Gene Name: SERPINA12

Full Name: Serpin family A member 12

Gene Symbol: OL-64

Gene ID: 145264

RefSeq ID-1: NP_001291390.1

RefSeq ID-2: NM_001304461.2

Summary: SERPINA12 encodes a secreted serine protease inhibitor predominantly expressed in adipose tissue. The protein has been implicated in the regulation of glucose metabolism, lipid processing, and insulin sensitivity. SERPINA12 is considered an adipokine with potential protective effects in obesity-related metabolic disorders.

LipoKnoxa™ Human SERPINA12 shRNA Lentiviral Particle (Silencing)

Product Overview

Specification

Target Profile

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