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Itraconazole
Cat. No.:
OB0225LY-0248
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Itraconazole is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes.
Synonym:
R51211; 84625-61-6; Sporanox; Oriconazole; Itraconazol; Itrizole; 2-Butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; 1-(Butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one; 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl); 4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS No.:
84625-61-6
Compound CID:
55283
Formula:
C35H38Cl2N8O4
Formula Weight:
705.63
Specification
Relative Density:
1.4 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Itraconazole can be used in microbiological studies to assess its inhibitory effect on fungal growth.
Library Information
Targets:
P450; Hedgehog/Smoothened
Receptors:
CYP3A4; Cytochrome P450
Pathways:
Metabolism; GPCR/G protein; Autophagy; Stem cells; Microbiology/Virology
Plate Number:
AOCL-4
Plate Location:
b3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
2 mM DMSO
DMSO Max Solubility:
7.06 mg/mL; 10 mM
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 0.71 mg/mL (1.01 mM)
ALogP:
6.434
HBA_Count:
7
HBD_Count:
0
Rotatable Bond:
11
