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Vitamin B12 test kit

TAK-715

Cat. No.: 0225LY-1054
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
TAK-715
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Product Overview

Description: TAK-715 acts as a targeted p38 MAPK inhibitor with specific activity against the p38α isoform.
Synonym: 303162-79-0; TAK 715; N-(4-(2-ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide; TAK715; Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-; N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]benzamide; Benzamide, N-(4-(2-ethyl-4-(3-methylphenyl)-5-thiazolyl)-2-pyridinyl)-; compound 8h (PMID: 16162000); N-(4-(2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)pyridin-2-yl)benzamide; T75
CAS No.: 303162-79-0
Compound CID: 9952773
Formula: C24H21N3OS
Formula Weight: 399.51

Specification

Targets&IC50: p38β: 0.20 μM; p38α: 7.1 nM
Relative Density: 1.233 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: TAK-715 can be used in autoimmune research to investigate the selective inhibition of p38 alpha MAPK and its effect on cytokine release.

Library Information

Target: Casein kinase; p38 MAPK; JNK
Receptor: Casein kinase; JNK1; p38α; p38β; p38γ; p38δ
Pathways: Metabolism; MAPK; Stem cell regulation
Plate Number: AOCL-14
Plate Location: e9
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 50 mg/mL; 125.15 mM
Ethanol Max Solubility: 20 mg/mL; 50.06 mM
ALogP: 5.629
HBA_Count: 3
HBD_Count: 1
Rotatable Bond: 5
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