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TAK-715
Cat. No.:
0225LY-1054
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
TAK-715 acts as a targeted p38 MAPK inhibitor with specific activity against the p38α isoform.
Synonym:
303162-79-0; TAK 715; N-(4-(2-ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide; TAK715; Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-; N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]benzamide; Benzamide, N-(4-(2-ethyl-4-(3-methylphenyl)-5-thiazolyl)-2-pyridinyl)-; compound 8h (PMID: 16162000); N-(4-(2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)pyridin-2-yl)benzamide; T75
CAS No.:
303162-79-0
Compound CID:
9952773
Formula:
C24H21N3OS
Formula Weight:
399.51
Specification
Targets&IC50:
p38β: 0.20 μM; p38α: 7.1 nM
Relative Density:
1.233 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TAK-715 can be used in autoimmune research to investigate the selective inhibition of p38 alpha MAPK and its effect on cytokine release.
Library Information
Target:
Casein kinase; p38 MAPK; JNK
Receptor:
Casein kinase; JNK1; p38α; p38β; p38γ; p38δ
Pathways:
Metabolism; MAPK; Stem cell regulation
Plate Number:
AOCL-14
Plate Location:
e9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 125.15 mM
Ethanol Max Solubility:
20 mg/mL; 50.06 mM
ALogP:
5.629
HBA_Count:
3
HBD_Count:
1
Rotatable Bond:
5





