Human tumor necrosis factor soluble receptor I (TNFSR-I) ELISA kit-Quantitative sandwich

Cat. No.: 0126WXX-1944

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: TNFSR-I

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Human tumor necrosis factor soluble receptor I (TNFSR-I) ELISA kit-Quantitative sandwich

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Product Overview

Description: Human tumor necrosis factor soluble receptor I (TNFSR-I) ELISA kit-Quantitative sandwich is an ELISA-based in vitro research tool designed specifically for the quantitative detection of TNFSR-I in human samples with a range of 125-4000 pg/mL and a minimum detectable dose (sensitivity) of 10 pg/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on TNFSR-I antibody-TNFSR-I antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFSR-I antigen targets in samples.

Background: TNFSR-I is the free form released into the bloodstream following proteolytic cleavage of the membrane-bound TNF-RI receptor. TNF-RI is generally recognized as the primary receptor mediating tumor necrosis factor (TNF-α) signaling, playing a crucial role particularly in apoptosis, cytotoxicity, and inflammatory signaling pathways. TNFSR-I functions as a decoy receptor in the circulation, binding TNF-α to neutralize its activity and thereby modulate systemic inflammatory burden. It is associated with chronic inflammation, insulin resistance, and obesity.

Synonyms: sTNF-RI; TNFRSF1A

Applications: Human tumor necrosis factor soluble receptor I (TNFSR-I) ELISA kit-Quantitative sandwich is used to quantify TNFSR-I in undiluted original human body fluids, tissue homogenates, secretions, and feces samples of human, providing data to support research in a wide range of areas, including signal transduction, inflammation, obesity, and others.

Research Area: Signal Transduction; Inflammation; Obesity

Specification

Sample Type: Undiluted original human body fluids; Tissue homogenates; Secretions; Feces samples

Detection Range: 125-4000 pg/mL

Sensitivity: 10 pg/mL

Precision (Intra-assay): CV<15%

Precision (Inter-assay): CV<15%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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