Human tartrate-resistant acid phosphatase 5b (TRACP 5b) ELISA kit (0.5-16 U/L)

Cat. No.: 0126WXX-1987

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: TRACP 5b

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Human tartrate-resistant acid phosphatase 5b (TRACP 5b) ELISA kit (0.5-16 U/L)

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Product Overview

Description: Human tartrate-resistant acid phosphatase 5b (TRACP 5b) ELISA kit (0.5-16 U/L) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of TRACP 5b in human samples with a range of 0.5-16 U/L and a minimum detectable dose (sensitivity) of 0.1 U/L. The kit is highly sensitive and easy to use.

Assay Principle: This ELISA kit is designed strictly for laboratory research and is not intended for diagnostic, drug, or therapeutic use. The assay is specifically optimized to determine the concentration of TRACP-5b (the analyte) in undiluted Human serum, plasma, or tissue homogenates. Users should contact technical support regarding the compatibility of other biological sample types. This kit is specifically calibrated for biological samples and is not suitable for testing non-biological substances.

Background: TRACP 5B, a metallophosphoesterase located at 19p13.2, encodes a tartrate-resistant acid phosphatase (EC 3.1.3.2) essential for bone resorption and the negative regulation of inflammatory cytokines, including TNF and interleukin-1 beta. By dephosphorylating osteopontin and bone sialoprotein, it maintains skeletal integrity and immune homeostasis; consequently, inactivating mutations lead to SPENCDI, while its elevated expression serves as a biomarker for various leukemias and Gaucher disease. In the context of metabolic health, TRACP 5B is increasingly recognized for its role in obesity-driven chronic inflammation, as its regulation of osteopontin signaling and macrophage activity directly influences the adipose tissue remodeling and systemic insulin resistance associated with excessive weight gain.

Synonyms: ACP5; TRAP5b; SPENCDI; TRACP-5b

Applications: Human tartrate-resistant acid phosphatase 5b (TRACP 5b) ELISA kit (0.5-16 U/L) is used to quantify TRACP 5b in human samples, providing data to support research in a wide range of areas, including signal transduction, metabolism, obesity, and others.

Research Area: Signal transduction; Metabolism; Obesity

Specification

Sample Type: Human samples

Detection Range: 0.5-16 U/L

Sensitivity: 0.1 U/L

Precision (Intra-assay): CV<15%

Precision (Inter-assay): CV<15%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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