Horse nuclear receptor subfamily 3, group C, member 1 (NR3C1) ELISA kit

Cat. No.: 0126WXX-1171

Assay Type: Quantitative ELISA

Target Species: Horse

Assay Target: NR3C1

Size:

Horse nuclear receptor subfamily 3, group C, member 1 (NR3C1) ELISA kit

INQUIRY Datasheet MSDS

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Product Overview

Description: Horse nuclear receptor subfamily 3, group C, member 1 (NR3C1) ELISA kit is an ELISA-based in vitro research tool designed specifically for the quantitative detection of NR3C1 in horse samples. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on NR3C1 antibody-NR3C1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NR3C1 antigen targets in samples.

Background: Nuclear receptor subfamily 3, group C, member 1 (NR3C1) is the scientific term for the glucocorticoid receptor (GR). It is a protein that functions as a nuclear receptor. Its primary role is to respond to a specific type of hormone called glucocorticoids—the most well-known of which is cortisol, often referred to as the “stress hormone.” When glucocorticoids enter cells, they bind to the GR. This binding activates the receptor, prompting it to migrate into the cell nucleus. Once inside the nucleus, GR directly attaches to specific regions of DNA, thereby turning on or off particular genes to regulate numerous biological processes in the body. It plays a central role in metabolism and serves as a key link between stress and obesity. Because it controls energy storage and expenditure, elevated cortisol levels resulting from chronic stress can overactivate this receptor, leading to weight gain. This effect is particularly pronounced in visceral fat—the dangerous fat that accumulates around abdominal organs.

Synonyms: GR; GCCR; GCR; GR; GRL; NR3-C1; Glucocorticoid receptor

Applications: Horse nuclear receptor subfamily 3, group C, member 1 (NR3C1) ELISA kit is used to quantify NR3C1 in horse samples, providing data to support research in a wide range of areas, including signal transduction, endocrinology, hormone metabolism, obesity, etc.

Research Area: Signal transduction; Endocrinology; Hormone metabolism; Obesity

Specification

Sample Type: Horse samples

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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