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GW6471
Cat. No.:
0225LY-0914
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
GW6471 functions as a PPARα antagonist (IC50: 0.24 μM) that increases the binding affinity between the PPARα ligand-binding domain and the co-repressor proteins NCoR and SMRT.
Synonym:
GW 6471; 880635-03-0; GW-6471; (S,Z)-N-(3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-((4-oxo-4-(4-(trifluoromethyl)phenyl)but-2-en-2-yl)amino)propyl)propionamide; N-[(2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-[[(Z)-4-oxo-4-[4-(trifluoromethyl)phenyl]but-2-en-2-yl]amino]propyl]propanamide; N-[(2S)-2-({(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]prop-1-en-1-yl}amino)-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propyl]propanamide; Propanamide, N-((2S)-2-(((1Z)-1-methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)-1-propenyl)amino)-3-(4-(2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy)phenyl)propyl)-; Propanamide, N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-
CAS No.:
880635-03-0
Compound CID:
446738
Formula:
C35H36F3N3O4
Formula Weight:
619.67
Specification
Relative Density:
1.204 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GW6471 can be used in molecular biology as a research tool to investigate the inhibition of PPAR-alpha mediated signaling.
Library Information
Target:
PPAR
Receptor:
PPARα
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
g5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
16.67 mg/mL; 26.9 mM





