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PI-828
Cat. No.:
0225LY-1498
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
PI-828 is utilized as a PI3K inhibitor to investigate physiological functions and to stimulate the differentiation of stem cells into the mesoderm.
Synonym:
LY 294002, 4gamma-NH2; 942289-87-4; PI 828; 8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one; LY294002 4'-NH2; 8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; 8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one; 8-(4-Aminophenyl)-2-(morpholin-4-yl)-4H-chromen-4-one; 8-(4-Aminophenyl)-2-(morpholin-4-yl)-4H-1-benzopyran-4-one
CAS No.:
942289-87-4
Compound CID:
25181195
Formula:
C19H18N2O3
Formula Weight:
322.36
Specification
Targets&IC50:
CK2α2: 1.127 μM; p110α: 173 nM; CK2: 149 nM
Relative Density:
1.316 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PI-828 can be used in cell biology to study the inhibition of the PI3K pathway and its effects on cell growth and survival.
Library Information
Target:
PI3K; Casein kinase
Receptor:
p110α; CK2; CK2α2
Pathways:
Metabolism; PI3K/Akt/mTOR signaling; Stem cell regulation
Plate Number:
AOCL-20
Plate Location:
c2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
11.2 mg/mL; 34.74 mM
