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Vitamin B12 test kit

Cinobufotalin

Cat. No.: 0225LY-1094
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
Cinobufotalin
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Product Overview

Description: Cinobufotalin is a major cardiac toxin from toads that functions as an anti-HCC agent by inducing apoptosis through ceramide production; it also reverses multidrug resistance and may enhance antiviral immunity in chronic hepatitis B patients.
Synonym: 1108-68-5; Cinobufagin metabolite m-2; 5-beta-Bufa-20,22-dienolide, 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-, 16-acetate; Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3beta,5beta,15beta,16beta)-; [(1R,2S,4R,5R,6R,7R,10S,11R,14S,16S)-14,16-dihydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate; (1R,2R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-dihydroxy-9a,11a-dimethyl-1-(2-oxo-2H-pyran-5-yl)hexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-2-yl acetate; Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-; (3ss,5ss,15ss,16ss)-16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-bufa-20,22-dienolide; ((1R,2S,4R,5R,6R,7R,10S,11R,14S,16S)-14,16-dihydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo(8.8.0.02,4.02,7.011,16)octadecan-5-yl) acetate; 14,16-Dihydroxy-7,11-dimethyl-6-(2-oxo-2H-pyran-5-yl)-3-oxapentacyclo(8.8.0.0,.0,.0,)octadecan-5-yl acetic acid
CAS No.: 1108-68-5
Compound CID: 259776
Formula: C26H34O7
Formula Weight: 458.54

Specification

Relative Density: 1.34 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Cinobufotalin can be used in cancer biology to examine its role in inducing apoptosis through the mitochondrial pathway.

Library Information

Target: MRP; IL receptor; Akt; P-gp
Receptor: Akt; IL receptor; MRP1; P-gp
Pathways: Cytoskeletal signaling; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling; Neuronal signaling; Immunology/Inflammation
Plate Number: AOCL-15
Plate Location: a10
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 50 mg/mL; 109.04 mM
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