AdipoUpX™ Human TBX3 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human TBX3 Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human TBX3 gene. This transcription factor is vital for researching the development of adipose tissue and its link to Ulnar-mammary syndrome and metabolic traits. The lentivirus characteristic of genome integration ensures a reliable cell model for studying cellular identity and adipocyte maturation. Comprehensive quality control, including titer and purity testing, is performed on all viral particles to ensure both product safety and experimental reliability.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: TBX3

Full Name: T-box transcription factor 3

Gene Symbol: UMS; XHL; TBX3-ISO

Gene ID: 6926

RefSeq ID-1: NP_005987.3

RefSeq ID-2: NM_005996.3

Summary: TBX3 is a member of the T-box family of transcription factors, acting primarily as a transcriptional repressor during development. It is crucial for limb patterning and the development of the mammary glands and teeth. Mutations in TBX3 cause ulnar-mammary syndrome, while its role in metabolic tissues is increasingly linked to energy balance regulation.

AdipoUpX™ Human TBX3 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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