AdipoUpX™ Human PPY MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PPY MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the stable overexpression of the human PPY gene. Pancreatic Polypeptide is a key regulator of appetite and gastric motility; its stable genomic integration is essential for studying satiety signaling in dividing host cells. All particles undergo rigorous quality control screening to ensure experimental reliability. Clients can freely customize key functional components to meet diverse experimental needs through our high-flexibility vector system.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: PPY

Full Name: Pancreatic polypeptide

Gene Symbol: PH; PP; PNP

Gene ID: 5539

RefSeq ID-1: NP_002713.1

RefSeq ID-2: NM_002722.5

Summary: PPY produces pancreatic polypeptide, a hormone synthesized in the islets of Langerhans that regulates gastrointestinal function and suppresses appetite. Its plasma levels are often reduced in individuals with hyperphagia (overeating) and elevated in those with anorexia. Studies in models of obesity suggest that PPY infusion can successfully reduce weight gain by enhancing satiety signals.

AdipoUpX™ Human PPY MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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