AdipoUpX™ Human MCHR1 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MCHR1 MMLV Particle (Overexpression) is a ready-to-use retroviral vector particle professionally engineered for the stable overexpression of the human MCHR1 gene. This receptor is a central target for studying melanin-concentrating hormone-mediated feeding behavior and energy balance. By enabling stable integration into dividing host cells, this tool facilitates the study of GPCR signaling in permanent cell models. All viral particle products undergo comprehensive quality control, including titer and mycoplasma testing, ensuring experimental safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: MCHR1

Full Name: Melanin concentrating hormone receptor 1

Gene Symbol: SLC1; GPR24; MCH1R; SLC-1; MCH-1R

Gene ID: 2847

RefSeq ID-1: NP_005288.3

RefSeq ID-2: NM_005297.3

Summary: MCHR1 encodes a G-protein-coupled receptor that binds melanin-concentrating hormone (MCH), a powerful appetite stimulant in the brain. The receptor modulates intracellular calcium flux and cAMP levels to drive feeding behavior. Because of its central role in the neuronal regulation of food consumption, MCHR1 is a prominent target for pharmacological interventions against obesity.

AdipoUpX™ Human MCHR1 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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