AdipoUpX™ Human PHF21A MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PHF21A MSCV Particle (Overexpression) provides stable overexpression of the human PHF21A gene, a chromatin-associated regulator involved in transcriptional control and neurodevelopment. Emerging evidence links PHF21A-related pathways to neuroendocrine regulation of body weight. The MSCV retroviral vector enables sustained gene expression across stem cells and additional mammalian cell systems. Viral quality is verified through titer assessment and sterility and mycoplasma testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: PHF21A

Full Name: PHD finger protein 21A

Gene Symbol: BHC80; NEDMS; BM-006; IDDBCS

Gene ID: 51317

RefSeq ID-1: NP_001095272.1

RefSeq ID-2: NM_001101802.3

Summary: PHF21A encodes a chromatin-associated protein that is a component of a histone deacetylase–containing transcriptional repressor complex. By regulating gene silencing through neuron-restrictive regulatory elements, PHF21A influences cell identity and differentiation. Emerging evidence suggests that epigenetic regulators such as PHF21A may indirectly contribute to metabolic regulation and obesity through long-term control of gene expression programs.

AdipoUpX™ Human PHF21A MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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