AdipoUpX™ Human MC2R Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MC2R Lentiviral Particle (Overexpression) is professionally engineered for the efficient and long-lasting overexpression of the human MC2R gene. As the specific receptor for ACTH, it is a key asset for studying the adrenal-adipose axis and the influence of cortisol on fat distribution. Genome integration ensures the target gene establishes a permanent presence for longitudinal functional validation. Every batch is verified through comprehensive quality control screening (titer, sterility, and mycoplasma), ensuring that experimental results are repeatable and safe.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: MC2R

Full Name: Melanocortin 2 receptor

Gene Symbol: ACTHR

Gene ID: 4158

RefSeq ID-1: NP_000520.1

RefSeq ID-2: NM_000529.2

Summary: MC2R is a member of the melanocortin receptor family that is uniquely sensitive to adrenocorticotropic hormone (ACTH). It is expressed in the adrenal cortex, where it triggers the production of glucocorticoids. Mutations in this receptor lead to familial glucocorticoid deficiency, disrupting the hormonal axis that regulates stress and metabolic energy allocation.

AdipoUpX™ Human MC2R Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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