AdipoUpX™ Human KIF7 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human KIF7 MSCV Particle (Overexpression) is engineered for stable expression of the human KIF7 gene, a ciliary protein involved in Hedgehog signaling. Ciliary signaling pathways are increasingly recognized for their role in energy balance and obesity. The MSCV vector enables robust gene integration in stem cells and other mammalian cell systems. Comprehensive QC screening ensures reproducible and safe experimental use.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: KIF7

Full Name: Kinesin family member 7

Gene Symbol: ACLS; AGBK; HLS2; MMEDF; JBTS12; UNQ340

Gene ID: 374654

RefSeq ID-1: NP_940927.2

RefSeq ID-2: NM_198525.3

Summary: KIF7 encodes a cilia-associated kinesin protein that serves as a critical regulator of the Sonic Hedgehog (SHH) signaling pathway. It organizes GLI transcription factors to either activate or repress gene expression depending on the presence of signaling ligands. As a ciliopathy-associated gene, KIF7 is involved in the developmental pathways that often intersect with syndromic obesity.

AdipoUpX™ Human KIF7 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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