AdipoUpX™ Human FASN MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FASN MMLV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human FASN gene. Fatty Acid Synthase is a central enzyme in the de novo lipogenesis pathway, making it a primary focus in obesity and fatty liver research. The MMLV vector ensures long-lasting overexpression in dividing host cells for high-throughput screening and functional validation. Product quality is ensured by rigorous purification and comprehensive QC screening, providing a safe, repeatable, and reliable research tool.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: FASN

Full Name: Fatty acid synthase

Gene Symbol: FAS; OA-519; SDR27X1

Gene ID: 2194

RefSeq ID-1: NP_004095.4

RefSeq ID-2: NM_004104.4

Summary: FASN encodes a massive, multifunctional enzyme system responsible for de novo lipogenesis. Its primary task is to synthesize palmitate from acetyl-CoA and malonyl-CoA. In a metabolic context, FASN is the machinery that converts excess dietary carbohydrates into storable fat. While essential for normal energy storage, its overactivity is linked to fat accumulation in the liver and has also been implicated in the survival of various cancer cell lines.

AdipoUpX™ Human FASN MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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