AdipoUpX™ Human DGAT2 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human DGAT2 MSCV Particle (Overexpression) enables stable overexpression of the human DGAT2 gene, a key enzyme catalyzing triglyceride synthesis. DGAT2 plays a central role in lipid storage and adipocyte biology, making it highly relevant for obesity research. The MSCV system supports long-term expression in stem cells, hematopoietic stem cells, and additional mammalian cell lines. Each product is subjected to full quality control screening.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: DGAT2

Full Name: Diacylglycerol O-acyltransferase 2

Gene Symbol: ARAT; HMFN1045; GS1999FULL

Gene ID: 84649

RefSeq ID-1: NP_001240820.1

RefSeq ID-2: NM_001253891.2

Summary: DGAT2 catalyzes the final and essential step in triglyceride synthesis by joining diacylglycerol with fatty acyl-CoAs. Unlike its counterpart DGAT1, this enzyme operates effectively at low magnesium concentrations. As the primary engine for creating storage fat, DGAT2 is a major focus for research into obesity, fatty liver disease, and lipid droplet formation.

AdipoUpX™ Human DGAT2 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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