AdipoUpX™ Human ADIPOR1 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ADIPOR1 MSCV Particle (Overexpression) is a high-titer retroviral tool engineered for the stable and efficient expression of adiponectin receptor 1. This receptor is critical for activating AMPK and PPARα signaling pathways, which enhance fatty acid oxidation and glucose uptake. The MSCV system is optimized for high-level integration in hematopoietic stem cells, stem cells, and various mammalian cell lines, making it ideal for metabolic research. To ensure experimental reproducibility and safety, every batch undergoes comprehensive quality control, including titer, sterility, and mycoplasma testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: ADIPOR1

Full Name: Adiponectin receptor 1

Gene Symbol: CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A

Gene ID: 51094

RefSeq ID-1: NP_001277482.1

RefSeq ID-2: NM_001290553.2

Summary: ADIPOR1 encodes a primary receptor for adiponectin, an adipose-derived hormone that orchestrates glucose levels and fatty acid catabolism. The binding of adiponectin to this receptor activates the AMP-activated protein kinase (AMPK) signaling pathway, which enhances insulin sensitivity and stimulates fatty acid oxidation. Consequently, it is a key molecular link between adipose tissue signals and systemic metabolic efficiency.

AdipoUpX™ Human ADIPOR1 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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