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TUG-499
Cat. No.:
0225LY-0847
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
TUG-499 is a selective agonist for the free fatty acid receptor 1 (FFAR1/GPR40) with an EC50 of 7.39; it is a valuable tool for Type 2 diabetes research due to its superior affinity for FFAR1 over various transporters, ion channels, and related receptors like PPARγ, FFA2, and FFA3.
Synonym:
1206629-08-4
CAS No.:
1206629-08-4
Compound CID:
54669771
Formula:
C16H11Cl2NO2
Formula Weight:
320.17
Specification
Targets&IC50:
FFAR1/GPR40: 7.39(pEC50)
Relative Density:
1.42 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TUG-499 can be used in metabolic studies to evaluate the selective agonism of the GPR120 receptor.
Library Information
Target:
GPR; PPAR
Receptor:
GPR40; FFA2; PPARγ
Pathways:
Endocrinology/Hormones; GPCR/G protein signaling; Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
h6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
22.5 mg/mL; 70.28 mM
