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Pranlukast
Cat. No.:
0225LY-0792
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Pranlukast acts as a cysteinyl leukotriene receptor-1 antagonist used to alleviate or prevent bronchospasms, particularly in asthmatic patients experiencing allergic reactions to environmental allergens.
Synonym:
103177-37-3; N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide; 4-Oxo-8-(4-(4-phenylbutoxy)benzoylamino)-2-(tetrazol-5-yl)-4H-1-benzopyran; N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-p-(4-phenylbutoxy)benzamide; N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-4-(4-phenylbutoxy)benzamide; 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran
CAS No.:
103177-37-3
Compound CID:
4887
Formula:
C27H23N5O4
Formula Weight:
481.5
Specification
Targets&IC50:
LTD4: 0.99 nM (Ki); LTC4: 5640 nM (Ki); LTE4: 0.63 nM (Ki)
Relative Density:
1.374 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pranlukast can be used in respiratory research to study the antagonism of cysteinyl leukotriene receptors in asthma models.
Library Information
Target:
NF-κB; IL receptor; Leukotriene receptor; TNF; LTR
Receptor:
CysLTR; IL-5; Leukotriene receptor; Mucin-2; NF-κB; TNF-α
Pathways:
Immunology/Inflammation; GPCR/G protein signaling; Apoptosis; NF-κB
Plate Number:
AOCL-11
Plate Location:
b11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
45 mg/mL; 93.46 mM
