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Crizotinib hydrochloride
Cat. No.:
OB0225LY-0297
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Crizotinib hydrochloride is a small molecule inhibitor that primarily targets specific tyrosine kinases with selective inhibition of tumor cells.
Synonym:
PF-02341066 hydrochloride; 1415560-69-8; Crizotinib (hydrochloride); 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, hydrochloride (1:1); 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine; hydrochloride; 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine--hydrogen chloride (1/1)
CAS No.:
1415560-69-8
Compound CID:
71576688
Formula:
C21H23Cl3FN5O
Formula Weight:
486.8
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Crizotinib hydrochloride can be used to study tumor biomarkers.
Library Information
Targets:
PKTs
Receptors:
ALK; c-Met/HGFR; ROS Kinase
Pathways:
Immunology/Inflammation; Angiogenesis; Tyrosine kinase/adaptors; Autophagy
Plate Number:
AOCL-4
Plate Location:
g8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
10 mg/mL; 20.54 mM
Water Max Solubility:
50 mg/mL; 102.71 mM
