Porcine nuclear receptor subfamily 1, group H, member 4 (NR1H4) ELISA kit-Quantitative sandwich

Cat. No.: 0126WXX-1154

Assay Type: Quantitative sandwich ELISA

Target Species: Porcine

Assay Target: NR1H4

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Porcine nuclear receptor subfamily 1, group H, member 4 (NR1H4) ELISA kit-Quantitative sandwich

INQUIRY Datasheet MSDS

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Product Overview

Description: Porcine nuclear receptor subfamily 1, group H, member 4 (NR1H4) ELISA kit-Quantitative sandwich is an ELISA-based in vitro research tool designed specifically for the quantitative detection of NR1H4 in porcine samples with a range of 0.25-8 ng/mL and a minimum detectable dose (sensitivity) of 0.1 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on NR1H4 antibody-NR1H4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NR1H4 antigen targets in samples.

Background: NR1H4 (also known as FXR) is a nuclear receptor acting as a bile acid sensor. Upon activation, FXR inhibits bile acid synthesis and broadly regulates lipid and glucose metabolism genes in the liver and intestine. In obesity and metabolic syndrome, FXR dysfunction impacts fat and glucose utilization, energy expenditure, and gut microbiota, making it a key therapeutic target for non-alcoholic fatty liver disease (NAFLD) and metabolic disorders.

Synonyms: BAR; FXR; HRR1; HRR-1; RIP14; Farnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14; RXR-interacting protein 14

Applications: Porcine nuclear receptor subfamily 1, group H, member 4 (NR1H4) ELISA kit-Quantitative sandwich is used to quantify NR1H4 in serum, plasma, whole blood, tissue, saliva, urine, feces, and other fluids of pig, providing data to support research in a wide range of areas, including metabolism, obesity, etc.

Research Area: Metabolism; Obesity

Specification

Sample Type: Serum; Plasma; Whole blood; Other fluid; Tissue; Saliva; Urine; Feces

Detection Range: 0.25-8 ng/mL

Sensitivity: 0.1 ng/mL

Precision (Intra-assay): CV<15%

Precision (Inter-assay): CV<15%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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