Porcine hormone sensitive lipase (LIPE) ELISA kit-Quantitative sandwich

Cat. No.: 0126WXX-427

Assay Type: Quantitative sandwich ELISA

Target Species: Porcine

Assay Target: LIPE

Size:

Porcine hormone sensitive lipase (LIPE) ELISA kit-Quantitative sandwich

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Porcine hormone sensitive lipase (LIPE) ELISA kit (116,598 Da) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of LIPE in porcine samples. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on LIPE antibody-LIPE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LIPE antigen targets in samples.

Background: LIPE, as a rate-limiting lipolytic enzyme, plays a pivotal role in lipid metabolism. It primarily hydrolyzes triglycerides stored in adipose tissue and cardiac muscle, converting them into free fatty acids. LIPE activity undergoes precise hormonal regulation: it is rapidly activated via cAMP-dependent phosphorylation under catecholamine influence, while insulin promotes its dephosphorylation and inactivation. Additionally, LIPE functions in steroid-producing tissues, converting cholesterol esters into cholesterol for steroid hormone synthesis. LIPE plays a pivotal role in the onset and progression of obesity, serving as the key rate-limiting enzyme in lipolysis. Its core function is to promote fat breakdown, releasing triglycerides stored within adipocytes for the body to utilize as energy. Obesity is frequently associated with abnormal regulation of LIPE activity within fat cells. Imbalances in its activity and regulation constitute a major molecular mechanism underlying fat accumulation and obesity.

Synonyms: HSL; LHS; Lipase, hormone sensitive; EC 3.1.1.79

EC NO.: 3.1.1.79

Applications: Porcine hormone sensitive lipase (LIPE) ELISA kit (116,598 Da) is used to quantify LIPE in porcine samples, providing data to support research in a wide range of areas, including metabolism, obesity, and others.

Research Area: Metabolism; Obesity

Specification

Sample Type: Porcine samples

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

Related Products

Inquiry

Inquiry Basket

Delete selected Check Out