Pigeon tumor necrosis factor soluble receptor II (TNFSR-II) ELISA kit

Cat. No.: 0126WXX-1967

Assay Type: Quantitative ELISA

Target Species: Pigeon

Assay Target: TNFSR-II

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Pigeon tumor necrosis factor soluble receptor II (TNFSR-II) ELISA kit

INQUIRY Datasheet MSDS

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Product Overview

Description: Pigeon tumor necrosis factor soluble receptor II (TNFSR-II) ELISA kit is an ELISA-based in vitro research tool designed specifically for the quantitative detection of TNFSR-II in pigeon samples. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on TNFSR-II antibody-TNFSR-II antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFSR-II antigen targets in samples.

Background: TNFSR-II is the free form released into the bloodstream following proteolytic cleavage of the membrane-bound TNF-RII receptor (TNFRSF1B). TNFSR-II primarily functions as a decoy receptor, capable of binding circulating tumor necrosis factor TNF-α to neutralize its activity and reduce its binding to membrane-bound receptors, thereby negatively regulating systemic inflammation. In obesity research, serum TNFSR-II concentration is a recognized and reliable biomarker of chronic low-grade inflammation and endothelial dysfunction. Elevated TNFSR-II levels are significantly associated with central obesity, insulin resistance, metabolic syndrome, and subsequent cardiovascular disease risk. Consequently, it is frequently used to assess inflammatory burden and disease progression in obese patients.

Synonyms: TNFsr-II; sTNFR2

Applications: Pigeon tumor necrosis factor soluble receptor II (TNFSR-II) ELISA kit is used to quantify TNFSR-II in pigeon samples, providing data to support research in a wide range of areas, including inflammation, metabolism, obesity, and others.

Research Area: Inflammation; Metabolism; Obesity

Specification

Sample Type: Pigeon samples

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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