Mouse pyruvate dehydrogenase E1 component subunit beta; mitochondrial (PDHB) ELISA kit

Cat. No.: 0126WXX-1250

Assay Type: Quantitative ELISA

Target Species: Mouse

Assay Target: PDHB

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Mouse pyruvate dehydrogenase E1 component subunit beta; mitochondrial (PDHB) ELISA kit

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Product Overview

Description: Mouse pyruvate dehydrogenase E1 component subunit beta; mitochondrial (PDHB) ELISA kit is an ELISA-based in vitro research tool designed specifically for the quantitative detection of PDHB in mouse samples. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on PDHB antibody-PDHB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDHB antigen targets in samples.

Background: PDHB is a key catalytic subunit of the pyruvate dehydrogenase complex (PDHC) in the mitochondrial matrix. This complex catalyzes the oxidative decarboxylation of pyruvate to produce acetyl-CoA, thereby directing glycolytic products into the tricarboxylic acid (TCA) cycle. This represents the core rate-limiting step in glucose metabolism. PDHB regulates cellular substrate selection between lipid and glucose oxidation, which is crucial for maintaining energy balance. Research indicates it plays a key role in conditions such as obesity.

Synonyms: PDHBD; PHE1B; E1beta; PDHE1B; PDHE1-B

Applications: Mouse pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) ELISA kit is used to quantify PDHB in mouse samples, providing data to support research in a wide range of areas, including mitochondrial function and energy metabolism, signal transduction, obesity, and others.

Research Area: Mitochondrial function and energy metabolism; Metabolism; Signal transduction; Obesity

Specification

Sample Type: Mouse samples

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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