Mouse glucose regulated protein 78 (GRP78) ELISA kit (0.156-10 ng/mL)

Cat. No.: 0126WXX-436

Assay Type: Quantitative sandwich ELISA

Target Species: Mouse

Assay Target: GRP78

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Mouse glucose regulated protein 78 (GRP78) ELISA kit (0.156-10 ng/mL)

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Product Overview

Description: Mouse glucose regulated protein 78 (GRP78) ELISA kit (0.156-10 ng/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of GRP78 in mouse samples with a range of 0.156-10 ng/mL and a minimum detectable dose (sensitivity) of 0.054 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on GRP78 antibody-GRP78 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRP78 antigen targets in samples.

Background: GRP78 is a molecular chaperone protein that plays a crucial role within the endoplasmic reticulum (ER). Its primary function is to assist in the proper folding and assembly of newly synthesized proteins while ensuring protein quality control. GRP78 may exert its effects by influencing the activity of obesity-related factors, thereby playing a role in diseases such as obesity. By studying and modulating GRP78 expression, scientists can gain a deeper understanding of obesity and its associated complications, paving the way for potential interventions.

Synonyms: MIF2; BIP; Immunoglobulin heavy chain-binding protein; Binding immunoglobulin protein; Endoplasmic reticulum lumenal Ca binding grp78; Heat shock 70kDa protein 5; HSPA5

Applications: Mouse glucose regulated protein 78 (GRP78) ELISA kit (0.156-10 ng/mL) is used to quantify GRP78 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates, and other biological fluids of mice, providing data to support research in a wide range of areas, including signal transduction, infection immunity, obesity, and others.

Research Area: Signal transduction; Infection immunity; Obesity