Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
Lomitapide mesylate
Cat. No.:
0225LY-1244
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Lomitapide mesylate is the methanesulfonic acid salt form of lomitapide, which serves as a small molecule inhibitor of MTP.
Synonym:
BMS-201038 mesylate; AEGR-733 mesylate; 202914-84-9; BMS 201038-04; Aegr-733 mesilate; BMS-201038-04; Lomitapide (mesylate); Lomitapide mesilate; 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-(4-(4-(((4'-(trifluoromethyl)(1,1'-biphenyl)-2-yl)carbonyl)amino)-1-piperidinyl)butyl)-, methanesulfonate; N-(2,2,2-trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide methanesulfonate; N-(2,2,2-trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)biphenyl-2-ylcarboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide methanesulfonate
CAS No.:
202914-84-9
Compound CID:
11274333
Formula:
C40H41F6N3O5S
Formula Weight:
789.83
Specification
Targets&IC50:
MTP: 8 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Lomitapide mesylate can be used in lipid metabolism research to study the systemic reduction of apolipoprotein B-containing lipoproteins.
Library Information
Target:
MTP
Receptor:
MTTP
Pathways:
Metabolism
Plate Number:
AOCL-16
Plate Location:
h11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
122 mg/mL; 154.46 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
93 mg/mL; 117.75 mM





