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Jaceosidin
Cat. No.:
0225LY-0540
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Jaceosidin is a microglial inhibitor and antioxidant that reduces neuroinflammation and T cell activation through the IFN-γ/STAT1/T-bet pathway; in endometrial cancer, it induces G2/M cell cycle arrest via the ERK/ATM/Chk1/2 axis, though its metabolism is highly dependent on CYP1A2 and UGT variants.
Synonym:
18085-97-7; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-chromen-4-one; 4',5,7-Trihydroxy-3',6-dimethoxyflavone; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-
CAS No.:
18085-97-7
Compound CID:
5379096
Formula:
C17H14O7
Formula Weight:
330.29
Specification
Relative Density:
1.483 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Jaceosidin can be used in immunology research to explore its role in suppressing the expression of pro-inflammatory cytokines.
Library Information
Target:
UGT; COX; BCL
Receptor:
Bcl-2 Family; COX; UGT
Pathways:
Immunology/Inflammation; Metabolism; Apoptosis; Neuronal signaling
Plate Number:
AOCL-8
Plate Location:
a4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 756.91 mM
Ethanol Max Solubility:
7.14 mg/mL; 21.62 mM
