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NTP42
Cat. No.:
0225LY-0922
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
NTP42 is an antagonist targeting the thromboxane A2 (TXA2) receptor, with a measured IC50 of 3.278 nM.
Synonym:
2055599-51-2; N-(tert-Butylcarbamoyl)-5-cyano-2-((4'-(difluoromethoxy)-[1,1'-biphenyl]-3-yl)oxy)benzenesulfonamide; NTP-42; 1-tert-butyl-3-[5-cyano-2-[3-[4-(difluoromethoxy)phenyl]phenoxy]phenyl]sulfonylurea; Benzenesulfonamide, 5-cyano-2-((4'-(difluoromethoxy)(1,1'-biphenyl)-3-yl)oxy)-N-(((1,1-dimethylethyl)amino)carbonyl)-; N-(tert-Butylcarbamoyl)-5-cyano-2-((4'-(difluoromethoxy)-(1,1'-biphenyl)-3-yl)oxy)benzenesulfonamide; 1-tert-butyl-3-(5-cyano-2-(3-(4-(difluoromethoxy)phenyl)phenoxy)phenyl)sulfonylurea
CAS No.:
2055599-51-2
Compound CID:
124147085
Formula:
C25H23F2N3O5S
Formula Weight:
515.53
Specification
Relative Density:
1.39 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
NTP42 can be used in respiratory research to evaluate its potential as an antagonist for the thromboxane prostanoid receptor in pulmonary hypertension.
Library Information
Target:
Prostaglandin receptor; PPAR
Receptor:
Prostaglandin receptor; TXA2R
Pathways:
Immunology/Inflammation; DNA damage/DNA repair; GPCR/G protein signaling; Metabolism
Plate Number:
AOCL-12
Plate Location:
h3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
30 mg/mL; 58.19 mM





