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Psoralidin
Cat. No.:
0225LY-1304
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Psoralidin possesses chemopreventive and anticancer attributes by transcriptionally inhibiting the activation of phosphatidylinositol 3-kinase and the phosphorylation of Akt.
Synonym:
18642-23-4; 3,9-Dihydroxy-2-prenylcoumestan; 3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one; 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro(3,2-c)(1)benzopyran-6-one; 3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one; 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihydroxy-2-(3-methyl-2-butenyl)-; 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one; 3,9-dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-(1)benzofuro(3,2-c)(1)benzopyran-6-one; 3,9-dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one; Psoralidin (5)
CAS No.:
18642-23-4
Compound CID:
5281806
Formula:
C20H16O5
Formula Weight:
336.34
Specification
Targets&IC50:
ERα: 1.03 μM; ERβ: 24.6 μM
Relative Density:
1.383 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Psoralidin can be used in antioxidant research or play an important role in studies concerning the inhibition of inflammatory cytokines and tumor cell growth.
Library Information
Target:
Estrogen/progestogen receptor; Lipoxygenase; Akt; Gamma-secretase; COX
Receptor:
Akt; COX; ERα; ERβ; Lipoxygenase; Notch; Phosphatidylinositol 3-kinase
Pathways:
Immunology/Inflammation; Stem cell regulation; NF-κB; Metabolism; Endocrinology/Hormones; Neuronal signaling; Cytoskeletal signaling; Microbiology/Virology; Proteases/Proteasome; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-17
Plate Location:
f11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55.56 mg/mL; 165.19 mM
Solubility:
Soluble in chloroform, dichloromethane, ethyl acetate, acetone, etc.
ALogP:
4.917
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
2
