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Curcumin
Cat. No.:
0225LY-0536
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Curcumin is a specific phenolic natural product that inhibits p300/CREB histone acetyltransferase (IC50 = 25 μM) and offers a vast range of antioxidant, anti-inflammatory, and antitumor activities.
Synonym:
Diferuloylmethane; Indian saffron; Turmeric yellow; 458-37-7; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
CAS No.:
458-37-7
Compound CID:
969516
Formula:
C21H20O6
Formula Weight:
368.3799
Specification
Targets&IC50:
p300 HAT: 25 μM
Relative Density:
0.93 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Curcumin can be used in a wide range of antioxidant and anti-inflammatory research, focusing on its ability to modulate multiple signaling molecules.
Library Information
Target:
Epigenetic reader; HDAC; Histone acetyltransferase
Receptor:
Epigenetic reader domain; Ferroptosis; Histone acetyltransferase; KEAP1-Nrf2; p300 histone acetylatransferase
Pathways:
Immunology/Inflammation; Apoptosis; Microbiology/Virology; Autophagy; Chromatin/Epigenetic; DNA damage/DNA repair
Plate Number:
AOCL-7
Plate Location:
h10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
265.00 mg/mL; 719.37 mM
Ethanol Max Solubility:
1.80 mg/mL; 4.89 mM
ALogP:
3.573
HBA_Count:
3
HBD_Count:
3
Rotatable Bond:
7
