Human very low-density lipoprotein receptor (VLDLR) ELISA kit (0.78-50 ng/mL)

Cat. No.: 0126WXX-2108

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: VLDLR

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Human very low-density lipoprotein receptor (VLDLR) ELISA kit (0.78-50 ng/mL)

INQUIRY Datasheet MSDS

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Product Overview

Description: Human very low-density lipoprotein receptor (VLDLR) ELISA kit (0.78-50 ng/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of VLDLR in human samples with a range of 0.78-50 ng/mL and a minimum detectable dose (sensitivity) of 0.23 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The microtiter plate provided in this kit is pre-coated with an antibody specific to the target antigen. Standards or samples are introduced into the appropriate wells along with a biotin-conjugated detection antibody and avidin-conjugated HRP. After incubation and subsequent washing, a TMB substrate solution is introduced. Color changes occur only in wells containing the target complex. The enzymatic reaction is stopped using a sulphuric acid solution, and the absorbance is recorded at 450 nm ± 2 nm. The concentration of the target antigen is determined by mapping the sample O.D. results against the provided standard curve.

Background: VLDLR, situated at chromosomal location 9p24, is a multifunctional transmembrane receptor essential for the clathrin-mediated endocytosis of VLDL and the orchestration of Reelin-driven signaling pathways during nervous system development. While its genetic defects are primarily linked to CMARQ1, characterized by cerebellar hypoplasia and developmental delays, its metabolic role is critical for lipid transport and systemic cholesterol homeostasis.

Synonyms: VLDL-R

Applications: Human very low-density lipoprotein receptor (VLDLR) ELISA kit (0.78-50 ng/mL) is used to quantify VLDLR in human samples, providing data to support research in a wide range of areas, including signal transduction, metabolic pathway, endocrinology, cardiovascular biology, hepatology, obesity, and others.

Research Area: Signal transduction; Metabolic pathway; Endocrinology; Cardiovascular biology; Hepatology; Obesity