Human small heterodimer partner (SHP) ELISA kit-Quantitative competitive

Cat. No.: 0126WXX-1795

Assay Type: Quantitative competitive ELISA

Target Species: Human

Assay Target: SHP

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Human small heterodimer partner (SHP) ELISA kit-Quantitative competitive

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Product Overview

Description: Human small heterodimer partner (SHP) ELISA kit-Quantitative competitive is an ELISA-based in vitro research tool designed specifically for the quantitative detection of SHP in human samples with a range of 1.0-25 ng/mL and a minimum detectable dose (sensitivity) of 0.1 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on SHP antibody-SHP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SHP antigen targets in samples.

Background: Small heterodimer partner (SHP, NR0B2) is a nuclear receptor that functions as a transcriptional corepressor, inhibiting the activity of other nuclear receptors and transcription factors by interfering with coactivator complexes. Through this regulation, SHP modulates metabolic pathways, including glucose and lipid metabolism. Dysregulation or defects in NR0B2 can impair energy balance and fat metabolism, contributing to the development of obesity.

Synonyms: NR0B2; SHP1; Nuclear receptor subfamily 0; Group B; Member 2; Orphan nuclear receptor SHP

Applications: Human small heterodimer partner (SHP) ELISA kit-Quantitative competitive is used to quantify SHP in serum, plasma, cell culture supernatants, body fluid, tissue homogenate of human, providing data to support research in a wide range of areas, including signal transduction, endocrinology, developmental science, hormone metabolism, obesity, and others.

Research Area: Signal transduction; Endocrinology; Developmental science; Hormone metabolism; Obesity

Specification

Sample Type: Serum; Plasma; Cell culture supernatants; Body fluid; Tissue homogenate

Detection Range: 1.0-25 ng/mL

Sensitivity: 0.1 ng/mL

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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