Human SH2B adapter protein 1 (SH2B1) ELISA kit-Quantitative sandwich

Cat. No.: 0126WXX-1787

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: SH2B1

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Human SH2B adapter protein 1 (SH2B1) ELISA kit-Quantitative sandwich

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Product Overview

Description: Human SH2B adapter protein 1 (SH2B1) ELISA kit-Quantitative sandwich is an ELISA-based in vitro research tool designed specifically for the quantitative detection of SH2B1 in human samples. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on SH2B1 antibody-SH2B1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SH2B1 antigen targets in samples.

Background: SH2B1 is an intracellular signaling adaptor protein. Its core function is to act as a signal amplifier for key metabolic hormone receptors such as insulin, leptin, and growth hormone, enhancing the activity of JAK2 and IRS proteins to sensitize downstream signaling pathways. As a pivotal hub in metabolic regulation, common variants in the SH2B1 gene are strongly associated with human obesity and insulin resistance, making it a core molecular target for studying the pathophysiology of obesity.

Synonyms: Pro-rich; PH and SH2 domain-containing signaling mediator (PSM); SH2 domain-containing protein 1B; KIAA1299, SH2B

Applications: Human SH2B adapter protein 1 (SH2B1) ELISA kit-Quantitative sandwich is used to quantify SH2B1 in serum, plasma, and other biological fluids of humans, providing data to support research in a wide range of areas, including neuroendocrinology, metabolism, cell growth and proliferation, and others.

Research Area: Neuroendocrinology; Metabolism; Cell growth and proliferation

Specification

Sample Type: Serum; Plasma; Other biological fluids

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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