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Euscaphic acid
Cat. No.:
0225LY-1131
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Euscaphic acid possesses anti-inflammatory and anti-diabetic traits, disrupting NF-κB activation by interfering with the clustering of TRAF6 with IRAK1 and TAK1.
Synonym:
53155-25-2; Acuminatic acid; Jacarandic acid; (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; NSC-733507; 2alpha,3alpha,19alpha-Trihydroxyurs-12-en-28-oic acid; (2alpha,3alpha)-2,3,19-trihydroxyurs-12-en-28-oic acid; Euscaphate; Jacarandate; Euscapic acid; Euscophic acid; (2alpha,3beta)-Isomer OF euscaphic acid
CAS No.:
53155-25-2
Compound CID:
471426
Formula:
C30H48O5
Formula Weight:
488.7
Specification
Targets&IC50:
DNA polymerase α (calf): 61 μM (IC50); DNA polymerase β (rat): 108 μM (IC50)
Relative Density:
1.19 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Euscaphic acid can be used in natural product research to explore its anti-inflammatory and potential anti-tumor biological activities.
Library Information
Target:
DNA/RNA synthesis; Prostaglandin receptor; LDL; PI3K; NO synthase
Receptor:
DNA/RNA synthesis; LDL; NO synthase; PGE; PI3K
Pathways:
Immunology/Inflammation; Apoptosis; Cell cycle/Checkpoint; Metabolism; GPCR/G protein signaling; DNA damage/DNA repair; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-15
Plate Location:
e7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 102.31 mM
