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Ervogastat
Cat. No.:
0225LY-0726
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Ervogastat is a well-tolerated and powerful inhibitor of DGAT2 that reduces hepatic triglycerides and steatosis in cases of non-alcoholic steatohepatitis (NASH).
Synonym:
2186700-33-2; Ervogastat; 2-(5-((3-Ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-((3S)-oxolan3-yl)pyrimidine-5-carboxamide; 5-Pyrimidinecarboxamide, 2-(5-((3-ethoxy-2-pyridinyl)oxy)-3-pyridinyl)-N-((3S)-tetrahydro-3-furanyl)-; 2-[5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl]-N-[(3S)-oxolan-3-yl]pyrimidine-5-carboxamide; (S)-2-(5-((3-ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide; 2-(5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl)-N-((3S)-oxolan-3-yl)pyrimidine-5-carboxamide
CAS No.:
2186700-33-2
Compound CID:
134262752
Formula:
C21H21N5O4
Formula Weight:
407.42
Specification
Relative Density:
1.36 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Ervogastat can be used in non-alcoholic steatohepatitis (NASH) research to evaluate the dual inhibition of DGAT2 and its effect on liver fat.
Library Information
Target:
DGAT2
Receptor:
DGAT2
Pathways:
Metabolism
Plate Number:
AOCL-10
Plate Location:
d3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
120 mg/mL; 294.54 mM





