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Dalcetrapib
Cat. No.:
0225LY-1241
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Dalcetrapib is a CETP inhibitor (IC50: 0.2 uM) that works to increase plasma concentrations of HDL cholesterol.
Synonym:
JTT-705; RO4607381; 211513-37-0; RO-4607381; S-[2-[[1-(2-ethylbutyl)cyclohexanecarbonyl]amino]phenyl] 2-methylpropanethioate; 2-Methylpropanethioic acid S-[2-[1-(2-ethylbutyl)cyclohexylcarboxamido]phenyl] ester; S-(2-(1-(2-ethylbutyl)cyclohexane-1-carboxamido)phenyl) 2-methylpropanethioate; S-[2-({[1-(2-ethylbutyl)cyclohexyl]carbonyl}amino)phenyl] 2-methylpropanethioate; S-(2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl) 2-methylpropanethioate; S-2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl 2-methylpropanethioate
CAS No.:
211513-37-0
Compound CID:
6918540
Formula:
C23H35NO2S
Formula Weight:
389.59
Specification
Targets&IC50:
CETP (recombinant human): 0.2 μM
Relative Density:
1.066 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Dalcetrapib can be used in metabolic research to explore the modulation of CETP activity and its role in high-density lipoprotein metabolism.
Library Information
Target:
CETP
Receptor:
rhCETP
Pathways:
Metabolism
Plate Number:
AOCL-16
Plate Location:
h8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
72 mg/mL; 184.81 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
72 mg/mL; 184.81 mM
ALogP:
7.025
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
9
