AdipoUpX™ Human PRKAA2 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PRKAA2 MMLV Particle (Overexpression) is a high-titer MMLV particle designed for the specific and stable overexpression of the human PRKAA2 (AMPK alpha 2) gene. This catalytic subunit of AMPK is a master sensor of cellular energy status; its stable integration is an ideal tool for investigating glucose uptake and lipid oxidation pathways. The viral system offers high flexibility for customization, and all particles pass through rigorous quality control—including titer and sterility validation—to ensure reliable research results.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: PRKAA2

Full Name: Protein kinase AMP-activated catalytic subunit alpha 2

Gene Symbol: AMPK; AMPK2; PRKAA; AMPKa2

Gene ID: 5563

RefSeq ID-1: NP_006243.2

RefSeq ID-2: NM_006252.3

Summary: PRKAA2 encodes the α2 catalytic subunit of AMP-activated protein kinase, a central cellular energy sensor. Activation of AMPKα2 suppresses anabolic lipid and cholesterol synthesis while promoting energy-generating pathways. This subunit plays a critical role in systemic insulin sensitivity and metabolic adaptation to energy stress.

AdipoUpX™ Human PRKAA2 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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